Gale, C. R., Hall, N. F., Phillips, D. I., and Martyn, C. N. Lutein and zeaxanthin status and risk of age-related macular degeneration. Long-term supplementation with alpha-tocopherol and beta-carotene and age-related cataract. Diabetes Care 2022;45(6):1453-1461. LaRowe, T. L., Mares, J. 1996;66(4):316-321. View abstract. 2001;74(6):796-802. Acta Ophthalmol.Scand. That is exactly why the lens needs to remain clear and free from the cloudiness that is indicative of cataracts. J Am Optom Assoc 1999;70:39-47. Am J Clin Nutr 1997;66:366-72. Fitzgerald KC, O'Reilly J, Fondell E, et al. Cancer Causes Control 1991;2:325-57. Li, L., Chen, C. Y., Aldini, G., Johnson, E. J., Rasmussen, H., Yoshida, Y., Niki, E., Blumberg, J. Biomed Res 2011;32(6):387-393. Mahmassani HA, Switkowski KM, Johnson EJ, et al. Pickup & Same Day Delivery available on most store items. View abstract. Hu, F., Wang, Yi B., Zhang, W., Liang, J., Lin, C., Li, D., Wang, F., Pang, D., and Zhao, Y. Carotenoids and breast cancer risk: a meta-analysis and meta-regression. View abstract. Teikari JM, Rautalahti M, Haukka J, et al. Clin.Chem. Cangemi, F. E. TOZAL Study: an open case control study of an oral antioxidant and omega-3 supplement for dry AMD. 2001;55(4):252-259. This amount can be obtained pretty easily by eating a healthy andhealing diet(one cup of kale has more than22 milligrams), but supplements are also recommended for people who are highly susceptible to eye damage, those who have digestive disorders that can hinder nutrient absorption and the elderly, who could use more protection. Edwards CG, Walk AM, Thompson SV, et al. Mewborn CM, Lindbergh CA, Hammond BR, Renzi-Hammond LM, Miller LS. Novel phytonutrient contributors to antioxidant protection against cardiovascular disease. View abstract. Reboul E, Thap S, Perrot E, et al. Am.J.Clin.Nutr. Nutr Res 2001;21:797-809. Ophthalmology 2008;115(2):334-341. View abstract. Olmedilla, B., Granado, F., Southon, S., Wright, A. J., Blanco, I., Gil-Martinez, E., Berg, H., Corridan, B., Roussel, A. M., Chopra, M., and Thurnham, D. I. Serum concentrations of carotenoids and vitamins A, E, and C in control subjects from five European countries. Chew EY, SanGiovanni JP, Ferris FL, et al. Nutrients. View abstract. Aside from protecting eyes, lutein uses also include helping prevent skin disorders, several types of cancer including colon or breast cancer, type 2 diabetes, and risk factors associated with coronary heart disease. 2013;91(1):6-11. View abstract. Asia Pac J Clin Nutr 2017;26(3):406-11. You can find lutein supplements in soft-gel capsule form in health food stores and online. Curran-Celentano, J., Hammond, B. R., Jr., Ciulla, T. A., Cooper, D. A., Pratt, L. M., and Danis, R. B. View abstract. Eye Disease Case-Control Study Group. Falsini, B., Piccardi, M., Iarossi, G., Fadda, A., Merendino, E., and Valentini, P. Influence of short-term antioxidant supplementation on macular function in age-related maculopathy: a pilot study including electrophysiologic assessment. Appl.Ergon. Am J Clin Nutr 2012;96(4):902-910. View abstract. View abstract. 12-19-2012;104(24):1905-1916. Br.J.Nutr. Even in people who have existing eye damage, including plenty of lutein in their diets can help stop the condition from progressing and further damaging vision. Palombo, P., Fabrizi, G., Ruocco, V., Ruocco, E., Fluhr, J., Roberts, R., and Morganti, P. Beneficial long-term effects of combined oral/topical antioxidant treatment with the carotenoids lutein and zeaxanthin on human skin: a double-blind, placebo-controlled study. View abstract. View abstract. WebFloraGLO Lutein is scientifically proven to be a valuable ingredient in maintaining the health of our skin by serving as an antioxidant and absorber of high-energy wavelengths of visible View abstract. Am J Clin Nutr 1999;69(2):272-277. Ophthalmology 2012;119(11):2282-2289. Invest Ophthalmol.Vis.Sci. Plasma carotenoids and vitamin C concentrations and risk of urothelial cell carcinoma in the European Prospective Investigation into Cancer and Nutrition. . Effect of long-chain ?-3 fatty acids and lutein + zeaxanthin supplements on cardiovascular outcomes: results of the Age-Related Eye Disease Study 2 (AREDS2) randomized clinical trial. The information in our articles is NOT intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. Korobelnik JF, Rougier MB, Delyfer MN, et al. Relation between dietary intake, serum concentrations, and retinal concentrations of lutein and zeaxanthin in adults in a Midwest population. Thomson, C. A., Stendell-Hollis, N. R., Rock, C. L., Cussler, E. C., Flatt, S. W., and Pierce, J. P. Plasma and dietary carotenoids are associated with reduced oxidative stress in women previously treated for breast cancer. 1996;126(9):2098-2106. A European multicentre, placebo-controlled supplementation study with alpha-tocopherol, carotene-rich palm oil, lutein or lycopene: analysis of serum responses. Retina 2008;28(1):103-110. With dry eye disease, also known as dry eye syndrome, your eyes dont make enough lubrication to coat your eyes. This can cause red, itchy, burning, eyes, temporary blurriness, and a feeling as if theres sand in your eye. According to a 2016 study, lutein may help reduce these symptoms. How much lutein do you need? View abstract. 2012;90(5):e399-e403. Macular yellow pigment. Hammond BR Jr, Miller LS, Bello MO, Lindbergh CA, Mewborn C, Renzi-Hammond LM. Vitamin A and carotenoids and the risk of Parkinson's disease: a systematic review and meta-analysis. Piermarocchi, S., Saviano, S., Parisi, V., Tedeschi, M., Panozzo, G., Scarpa, G., Boschi, G., and Lo, Giudice G. Carotenoids in Age-related Maculopathy Italian Study (CARMIS): two-year results of a randomized study. View abstract. Am.J.Clin.Nutr. View abstract. Calories 9.6 kcal Protein 0.51 g Fat 0.75 g Carbohydrate 0.24 g Sodium 00.012 g Lutein 18.0 mg Zeaxanthin 3.6 mg -cryptoxanthin 28.8 g -carotene 1080 g -carotene 270 g Lycopene 2.1 mg Bilberry extract 30.0 mg Blackcurrant extract 72.0 mg DHA 50.9 mg Vitamin B1 0.9 mg Glucosamine: 2 people, 18.18%. View abstract. Gouado, I., Schweigert, F. J., Ejoh, R. A., Tchouanguep, M. F., and Camp, J. V. Systemic levels of carotenoids from mangoes and papaya consumed in three forms (juice, fresh and dry slice). Cancer Epidemiol.Biomarkers Prev. View abstract. Saxena, S., Srivastava, P., and Khanna, V. K. Antioxidant supplementation improves platelet membrane fluidity in idiopathic retinal periphlebitis (Eales' disease). are clickable links to these studies. J Nutr 2006;136(5):1161-1165. A large body of evidence shows that lutein has several beneficial effects, especially on eye health. Dietary carotenoid intake and risk of developing preeclampsia: a hospital-based case-control study. Am J Hypertens. 2001;42(2):439-446. View abstract. Retina 1981;1(4):296-310. It may help decrease heart problems. View abstract. View abstract. 2013;54(3):1781-1788. Dietary lutein reduces ultraviolet radiation-induced inflammation and immunosuppression. Morganti, P., Fabrizi, G., and Bruno, C. Protective effects of oral antioxidants on skin and eye function. JAMA 2005;294:3101-7. Bone, R. A., Landrum, J. T., Dixon, Z., Chen, Y., and Llerena, C. M. Lutein and zeaxanthin in the eyes, serum and diet of human subjects. Changes in plasma amino acid patterns in chronic alcoholic patients during ethanol withdrawal syndrome: their clinical implications. Dietary lutein and cognitive function in adults: A meta-analysis of randomized controlled trials. Rubin, L. P., Chan, G. M., Barrett-Reis, B. M., Fulton, A. View abstract. 2013 Feb 15;5(2):543-51. Lopresti AL, Smith SJ, Drummond PD. 2002;132(12):3668-3673. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first. Lutein has no known severe, serious, moderate, or mild interactions with other drugs. This information does not contain all possible interactions or adverse effects. View abstract. Handelman, G. J., Nightingale, Z. D., Lichtenstein, A. H., Schaefer, E. J., and Blumberg, J. The most researched benefit of lutein is related to eye health, but it has also been linked to heart health, improved cognitive function, and reduced risk of certain types of cancer. This article explores everything you need to know about lutein, including food sources of it, supplements, health benefits, and potential risks. What is lutein? Sedating antihistamines are also called first-generation antihistamines because they were the first Wolf-Schnurrbusch UE, Zinkernagel MS, Munk MR, Ebneter A, Wolf S. Oral lutein supplementation enhances macular pigment density and contrast sensitivity but not in combination with polyunsaturated fatty acids. Ito, Y., Wakai, K., Suzuki, K., Ozasa, K., Watanabe, Y., Seki, N., Ando, M., Nishino, Y., Kondo, T., Ohno, Y., and Tamakoshi, A. Acta Ophthalmol Scand 1997;75:634-40. View abstract. Int J Food Sci Nutr 2016;67(7):744-53. View abstract. View abstract. This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Garca-Layana A, Recalde S, Alamn AS, Robredo PF. Graefes Arch Clin Exp Ophthalmol. View abstract. A case-control study. Maternal lutein and zeaxanthin concentrations in relation to offspring visual acuity at 3 years of age: The GUSTO Study. J.Nutr. Invest Ophthalmol.Vis.Sci. Am J Clin Nutr 2000;71:575-82. View abstract. 2012;22(2):216-225. Martin, K. R., Failla, M. L., and Smith, J. C., Jr. Beta-carotene and lutein protect HepG2 human liver cells against oxidant-induced damage. View abstract. Br.J Nutr 1999;82(3):203-212. View abstract. Hammond, B. R., Jr. and Fletcher, L. M. Influence of the dietary carotenoids lutein and zeaxanthin on visual performance: application to baseball. View abstract. Majumdar SK, Shaw GK, Thomson AD, et al. View abstract. Amount of fat in the diet affects bioavailability of lutein esters but not of alpha-carotene, beta-carotene, and vitamin E in humans. Invest Ophthalmol.Vis.Sci. Lutein is an orange-colored nutrient. Lutein /zeaxanthin for the treatment of age-related cataract: AREDS2 randomized trial report no. J.Nutr. J.Ocul.Pharmacol.Ther. View abstract. View abstract. 1998;7(6):537-544. Neutrogena Norwegian Formula Dry Hand Cream. J Sci Food Agric. Ophthalmology 2011;118(10):1958-1965. 2014 May;174(5):763-71. View abstract. Lutein bioavailability is higher from lutein-enriched eggs than from supplements and spinach in men. A 2009 study conducted on diabetic rats found that supplementing with lutein and DHA (a crucial type of omega-3 fatty acid) helped normalize all diabetes-induced biochemical modifications. Cho, E., Hankinson, S. E., Rosner, B., Willett, W. C., and Colditz, G. A. Vallverdu-Queralt, A., Martinez-Huelamo, M., Arranz-Martinez, S., Miralles, E., and Lamuela-Raventos, R. M. Differences in the carotenoid content of ketchups and gazpachos through HPLC/ESI(Li(+) )-MS/MS correlated with their antioxidant capacity. Ann Hematol 2017;96(6):957-65. View abstract. Influence of increased fruit and vegetable intake on plasma and lipoprotein carotenoids and LDL oxidation in smokers and nonsmokers. J Nutr 2003;133(1):98-101. View abstract. View abstract. . Am J Clin Nutr 1999;70:517-24. Mol.Nutr.Food Res. Cota F, Costa S, Giannantonio C, Purcaro V, Catenazzi P, Vento G. Lutein supplementation and retinopathy of prematurity: a meta-analysis. There arent any known special precautions for women who are pregnant or breastfeeding, but its always a good idea to speak with your doctor when pregnant before beginning new supplemental treatments. 2006;90(7):927-928. J Aging Res 2019;2019:3709402. Relationship of serum alpha-tocopherol, carotenoids and retinol with the risk of breast cancer. View abstract. 2010;128(4):403-411. Natarajan, L., Rock, C. L., Major, J. M., Thomson, C. A., Caan, B. J., Flatt, S. W., Chilton, J. 2002;132(3):525S-530S. View abstract. 2009;40(6):1047-1054. A., Liu, C., Tang, G., Krinsky, N. I., and Russell, R. M. Human plasma carotenoid response to the ingestion of controlled diets high in fruits and vegetables. Yeum, K. J., Booth, S. L., Sadowski, J. View abstract. View abstract. Herron, K. L., McGrane, M. M., Waters, D., Lofgren, I. E., Clark, R. M., Ordovas, J. M., and Fernandez, M. L. The ABCG5 polymorphism contributes to individual responses to dietary cholesterol and carotenoids in eggs. View abstract. View abstract. Bartlett, H., Howells, O., and Eperjesi, F. The role of macular pigment assessment in clinical practice: a review. Supplementation with carotenoids, omega-3 fatty acids, and vitamin E has a positive effect on the symptoms and progression of Alzheimer's disease. 2007;42(5):720-726. 2012;131(1):239-253. In the process, antioxidants like lutein protect healthy cells while halting the growth of malignant cells. Abnet, C. C., Qiao, Y. L., Dawsey, S. M., Buckman, D. W., Yang, C. S., Blot, W. J., Dong, Z. W., Taylor, P. R., and Mark, S. D. Prospective study of serum retinol, beta-carotene, beta-cryptoxanthin, and lutein/zeaxanthin and esophageal and gastric cancers in China. The following vitamins and minerals are particularly relevant for eczema: Zinc: Found in seafood, pumpkin seeds, dark choc, lean red meat Vitamin C: Found in brightly WebLutein & Zeaxanthin Eye Health Supplement for Adults - Delicious Vegan Eye Vitamins Lutein and Zeaxanthin Gummies - Zeaxanthin Plus Lutein 20mg for Vision Clarity Dry Eye Relief and Blue Light Support. Cardinault, N., Tyssandier, V., Grolier, P., Winklhofer-Roob, B. M., Ribalta, J., Bouteloup-Demange, C., Rock, E., and Borel, P. Comparison of the postprandial chylomicron carotenoid responses in young and older subjects. Lutein is an antioxidant often used in the treatment or prevention of eye diseases. Overall skin tone and skin-lightening-improving effects with oral supplementation of lutein and zeaxanthin isomers: a double-blind, placebo-controlled clinical trial. Chew EY, Clemons TE, Agrn E, et al. Nutrition 2012;28(6):605-610. A., Klein, M. L., Gehrs, K. M., Johnson, E. J., Snodderly, D. M., Wallace, R. B., Chappell, R. J., Parekh, N., Ritenbaugh, C., and Mares, J. View abstract. The human body cannot synthesize lutein or zeaxanthin on its own, which means we must obtain these important nutrients from our diets (or, in some cases, supplements). J.Nutr.Sci.Vitaminol. Gartner, C., Stahl, W., and Sies, H. Preferential increase in chylomicron levels of the xanthophylls lutein and zeaxanthin compared to beta-carotene in the human. J.Matern.Fetal Neonatal Med. Design: Subjects were 1290 mother-child pairs in an ongoing cohort study. View abstract. Curr.Pharm.Des 2012;18(34):5577-5589. View abstract. View abstract. Liu XH, Yu RB, Liu R, et al. View abstract. Mol.Nutr.Food Res. Creatine therapy in myophosphorylase deficiency (McArdle disease): a placebo-controlled crossover trial. View abstract. Schunemann HJ, Grant BJ, Freudenheim JL, et al. Kaya, S., Weigert, G., Pemp, B., Sacu, S., Werkmeister, R. M., Dragostinoff, N., Garhofer, G., Schmidt-Erfurth, U., and Schmetterer, L. Comparison of macular pigment in patients with age-related macular degeneration and healthy control subjects - a study using spectral fundus reflectance. Prostaglandins Other Lipid Mediat 2022;164:106691. View abstract. Med.Sci.Sports Exerc. View abstract. Xiong K, Zhao Y, Hu S, Ma A, Ma Y. Dose-response relationship between oral lutein intake and plasma lutein concentration: A randomized controlled trial. Am J Clin Nutr 1999;70(4):490-494. WebFor years, people have sworn that oil supplements can relieve dry, itchy eczema. View abstract. Dietary modification of human macular pigment density. Lutein + zeaxanthin and omega-3 fatty acids for age-related macular degeneration: the Age-Related Eye Disease Study 2 (AREDS2) randomized clinical trial. BMJ 10-13-2007;335(7623):755. Paetau, I., Rao, D., Wiley, E. R., Brown, E. D., and Clevidence, B. Modification of lymphocyte DNA damage by carotenoid supplementation in postmenopausal women. 2001;119(7):1009-1019. WebShop 12 Hour Mucus Relief DM Extended-Release Tablets Maximum Strength and read reviews at Walgreens. Shao, A. and Hathcock, J. N. Risk assessment for the carotenoids lutein and lycopene. View abstract. Am J Clin Nutr 2005;82(3):685-693. Breast Cancer Res.Treat. Arch.Biochem.Biophys. 2001;42(8):1873-1881. The recommended lutein dosage for preventing oxidative damage and lowering symptoms of eye or skin disorders isbetween 6 milligrams and 30 milligrams daily for adults, according to the American Macular Degeneration Association. View abstract. San Giovanni, J. P., Chew, E. Y., Clemons, T. E., Ferris, F. L., III, Gensler, G., Lindblad, A. S., Milton, R. C., Seddon, J. M., and Sperduto, R. D. The relationship of dietary carotenoid and vitamin A, E, and C intake with age-related macular degeneration in a case-control study: AREDS Report No. J Lab Clin Med 1999;134(6):592-598. Johnson, E. J. Nolan JM, Power R, Howard AN, et al. Chong, E. W., Wong, T. Y., Kreis, A. J., Simpson, J. View abstract. View abstract. Of those 20,zeaxanthin and lutein are the only two that are deposited in high quantities into the macular portion of the eyes. View abstract. Thurnham, D. I., Northrop-Clewes, C. A., Paracha, P. I., and McLoone, U. J. Cancer Epidemiol Biomarkers Prev 2003;12:518-26. View abstract. 26th ed. Invest Ophthalmol.Vis.Sci. It is thought to function as a light filter, protecting the eye tissues from sunlight damage. Ravindran, R. D., Vashist, P., Gupta, S. K., Young, I. S., Maraini, G., Camparini, M., Jayanthi, R., John, N., Fitzpatrick, K. E., Chakravarthy, U., Ravilla, T. D., and Fletcher, A. E. Inverse association of vitamin C with cataract in older people in India. View abstract. Bernstein, P. S., Ahmed, F., Liu, A., Allman, S., Sheng, X., Sharifzadeh, M., Ermakov, I., and Gellermann, W. Macular pigment imaging in AREDS2 participants: an ancillary study of AREDS2 subjects enrolled at the Moran Eye Center. Carotenoids are a group of naturally occurring pigments that are largely responsible for the red, yellow, and orange color of fruits and vegetables and some animals. You already know that filling up on plenty of fruits and veggies is good for you, and heres just another example of why that is. Zhao, X., Aldini, G., Johnson, E. J., Rasmussen, H., Kraemer, K., Woolf, H., Musaeus, N., Krinsky, N. I., Russell, R. M., and Yeum, K. J. Rapp, L. M., Maple, S. S., and Choi, J. H. Lutein and zeaxanthin concentrations in rod outer segment membranes from perifoveal and peripheral human retina. Prospective study of intake of fruits, vegetables, vitamins, and carotenoids and risk of age-related maculopathy. Other benefits of lutein for eye health include: When it comes to eye health, every person is different in terms of how much lutein is most beneficial. View abstract. Kobayashi J, Tominaga E, Ozeki M, Okubo T, Nakagawa K, Miyazawa T. Randomized controlled trial of a water-soluble formulation of lutein in humans. View abstract. JAMA Ophthalmol 2017;135(11):1259-1266. Ma, L., Lin, X. M., Zou, Z. Y., Xu, X. R., Li, Y., and Xu, R. A 12-week lutein supplementation improves visual function in Chinese people with long-term computer display light exposure. van Leeuwen R, Boekhoorn S, Vingerling JR, et al. According to the Centers for Disease Control and Prevention (CDC), Americans get American Macular Degeneration Association, Top 7 Ways Carrot & Carrot Juice Benefit Your Body, Daniel Fast: Benefits for Your Spiritual, Emotional and Physical Health, 15 Fermented Foods for a Healthy Gut and Overall Health, 9 Proven Black Seed Oil Benefits that Boost Your Health, L-Glutamine Benefits Leaky Gut & Metabolism, Chia Seeds Benefits: The Omega-3, Protein-Packed Superfood, Apple Cider Vinegar Benefits for Weight Loss, Skin Health, Cholesterol & More, Is Lamb Healthy? Olestra affects serum concentrations of alpha-tocopherol and carotenoids but not vitamin D or vitamin K status in free-living subjects. Holtan, S. G., O'Connor, H. M., Fredericksen, Z. S., Liebow, M., Thompson, C. A., Macon, W. R., Micallef, I. N., Wang, A. H., Slager, S. L., Habermann, T. M., Call, T. G., and Cerhan, J. R. Food-frequency questionnaire-based estimates of total antioxidant capacity and risk of non-Hodgkin lymphoma. However, at this time, more research is still needed to help us fully understand the effects of carotenoids on cancer, along with immune, hormonal and cardiovascular health, independent of other nutrients that are found in fruits and vegetables. Exp Eye Res 2004;79:21-27. Am.J.Clin.Nutr. 2012;53(12):7871-7880. Foods Baltimore, MD: Williams & Wilkins, 1995. 2006;124(8):1151-1162. Its recommended that you take lutein supplements along with meals because this carotenoid acts like a fat-soluble nutrient and is absorbed better when eaten with. Bone, R. A., Landrum, J. T., Mayne, S. T., Gomez, C. M., Tibor, S. E., and Twaroska, E. E. Macular pigment in donor eyes with and without AMD: a case-control study. A randomized trial of vitamin A and vitamin E supplementation for retinitis pigmentosa. Skin Pharmacol.Physiol 2007;20(4):199-210. 2004;80(1):131-136. View abstract. Juturu V, Bowman JP, Deshpande J. Overall skin tone and skin-lightening-improving effects with oral supplementation of lutein and zeaxanthin isomers: a double-blind, placebo-controlled clinical trial. Clin Cosmet Investig Dermatol 2016;9:325-332. View abstract. are clickable links to medically peer-reviewed studies. Mol.Nutr.Food Res. It's related to beta-carotene and vitamin A. Lutein-rich foods include egg yolks, broccoli, spinach, kale, corn, orange pepper, kiwi fruit, grapes, orange juice, zucchini and squash. Int.J.Cancer 9-1-2012;131(5):1158-1168. Li J, Abdel-Aal EM. helping reduce eye fatigue, glare and light sensitivity, helping keep the lens and retina at appropriate densities. Keep in mind that as with other antioxidants, people seem to differ in terms of how capable their bodies are of absorbing lutein. 2008;27(2):218-227. Ophthalmology 2001;108(11):1992-1998. Arch Neurol 2000;57:956-63. View abstract. Ophthalmic Surg Lasers Imaging Retina 2016;47(6):528-35. Optometry. 2014 Jan 22;6(1):452-65. View abstract. Biofactors 1999;10(2-3):105-113. 2000;46(11):1818-1829. Clin Nutr 2016;35(1):109-16. Am.J.Clin.Nutr. Am.J.Clin.Nutr. Curr Dev Nutr 2021;5(10):nzab123. Iribarren, C., Folsom, A. R., Jacobs, D. R., Jr., Gross, M. D., Belcher, J. D., and Eckfeldt, J. H. Association of serum vitamin levels, LDL susceptibility to oxidation, and autoantibodies against MDA-LDL with carotid atherosclerosis. View abstract. View abstract. Lutein is found in the retina, where it is thought to protect the eye from the View abstract. Am J Clin Nutr 1999;70:509-16. Invest Ophthalmol.Vis.Sci. Pool-Zobel, B. L., Bub, A., Muller, H., Wollowski, I., and Rechkemmer, G. Consumption of vegetables reduces genetic damage in humans: first results of a human intervention trial with carotenoid-rich foods. Johnson, E. J., McDonald, K., Caldarella, S. M., Chung, H. Y., Troen, A. M., and Snodderly, D. M. Cognitive findings of an exploratory trial of docosahexaenoic acid and lutein supplementation in older women. View abstract. View abstract. View abstract. View abstract. 1996;36(13):2001-2012. The Effects of Lutein and Zeaxanthin Supplementation on Brain Morphology in Older Adults: A Randomized, Controlled Trial. 2002;80(4):368-371. Andersen, L. F., Jacobs, D. R., Jr., Gross, M. D., Schreiner, P. J., Dale, Williams O., and Lee, D. H. Longitudinal associations between body mass index and serum carotenoids: the CARDIA study. Front Nutr 2022;9:924997. Eye Disease Case-Control Study Group. Can.J.Ophthalmol. Medicine (Baltimore) 2019;98(29):e15404. Hammond, B. R., Jr., Fuld, K., and Curran-Celentano, J. Macular pigment density in monozygotic twins. Thyagarajan, B., Meyer, A., Smith, L. J., Beckett, W. S., Williams, O. D., Gross, M. D., and Jacobs, D. R., Jr. Serum carotenoid concentrations predict lung function evolution in young adults: the Coronary Artery Risk Development in Young Adults (CARDIA) study. With strict editorial sourcing guidelines, we only link to academic research institutions, reputable media sites and, when research is available, medically peer-reviewed studies. JAMA Ophthalmol 2015;133(12):1415-24. Arch.Ophthalmol. BMC Ophthalmol 2007;7:3. Lutein uses and benefits include helping prevent eye conditions like macular degeneration and cataracts, skin disorders and skin cancer, several types of cancer, including colon or breast cancer, type 2 diabetes, and heart disease. View abstract. Yagi, A., Fujimoto, K., Michihiro, K., Goh, B., Tsi, D., and Nagai, H. The effect of lutein supplementation on visual fatigue: a psychophysiological analysis. Effect of Omega-3 Fatty Acids, Lutein/Zeaxanthin, or Other Nutrient Supplementation on Cognitive Function: The AREDS2 Randomized Clinical Trial. The risk of vision loss decreased by 19%. View abstract. View abstract. Cancer Epidemiol.Biomarkers Prev. Am J Clin Nutr 2003;78(5):985-992. View abstract. The effects of lutein and zeaxanthin supplementation on cognitive function in adults with self-reported mild cognitive complaints: A randomized, double-blind, placebo-controlled study. Cochrane Database Syst Rev. View abstract. Chew EY, Clemons TE, Agrn E, et al . View abstract. Therapeutic Research Faculty 2020. All rights reserved. Incidence of cataract operations in Finnish male smokers unaffected by alpha tocopherol or beta carotene supplements. Richer S, Stiles W, Statkute L, et al. Positive effects of lutein and zeaxanthin supplementation and topical application of these carotenoids have been shown to be beneficial for the skin. Berson EL, Rosner B, Sandberg MA, et al. 2005 - 2023 WebMD LLC. View abstract. View abstract. Dwyer, J. H., Navab, M., Dwyer, K. M., Hassan, K., Sun, P., Shircore, A., Hama-Levy, S., Hough, G., Wang, X., Drake, T., Merz, C. N., and Fogelman, A. M. Oxygenated carotenoid lutein and progression of early atherosclerosis: the Los Angeles atherosclerosis study. View abstract. View abstract. Effect of Dietary Supplementation With Lutein, Zeaxanthin, and ?-3 on Macular Pigment: A Randomized Clinical Trial. J Nutr.Biochem. J Nutr 2004;134:1887-93. Fruits and vegetables that are sources for lutein and zeaxanthin: the macular pigment in human eyes. J Perinatol. J Natl.Cancer Inst. View abstract. A., Meyer-Wenger, A., Moser, U., Wright, A., Southon, S., Thurnham, D., Chopra, M., van den, Berg H., Olmedilla, B., Favier, A. E., and Roussel, A. M. No significant effects of lutein, lycopene or beta-carotene supplementation on biological markers of oxidative stress and LDL oxidizability in healthy adult subjects. The possible significance of parallel changes in plasma lutein and retinol in Pakistani infants during the summer season. Kang T, Liu Y, Chen X, et al. Lutein and zeaxanthin intake during pregnancy and visual function in offspring at 11-12 years of age. A., Fisher, A. I., Klein, R., Palta, M., Block, G., Millen, A. E., and Wright, J. D. Lutein and zeaxanthin in the diet and serum and their relation to age-related maculopathy in the third national health and nutrition examination survey. View abstract. van der Horst-Graat JM, Kok, F. J., and Schouten, E. G. Plasma carotenoid concentrations in relation to acute respiratory infections in elderly people. Ophthalmologica 2017;237(3):159-66. Br.J.Nutr. This carotenoid is obtained from both foods and supplements, which are generally considered safe. 2013 Jul;131(7):843-50. Eliassen, A. H., Hendrickson, S. J., Brinton, L. A., Buring, J. E., Campos, H., Dai, Q., Dorgan, J. F., Franke, A. Some animal studies show evidence that lutein offers significant protection against light-induced skin damage, such as signs of aging and potentially skin cancer. Teikari JM, Virtamo J, Rautalahti M, et al. Dherani, M., Murthy, G. V., Gupta, S. K., Young, I. S., Maraini, G., Camparini, M., Price, G. M., John, N., Chakravarthy, U., and Fletcher, A. E. Blood levels of vitamin C, carotenoids and retinol are inversely associated with cataract in a North Indian population. View abstract. J Nutr 2002;132:3668-73. Wang X, Jiang C, Zhang Y, et al. Takeda, S., Masuda, Y., Usuda, M., Marushima, R., Ueji, T., Hasegawa, M., and Maruyama, C. Effects of mayonnaise on postprandial serum lutein/zeaxanthin and beta-carotene concentrations in humans. Influence of feeding different vegetables on plasma levels of carotenoids, folate and vitamin C. Effect of disruption of the vegetable matrix. View abstract. Feng L, Nie K, Jiang H, Fan W. Effects of lutein supplementation in age-related macular degeneration. Williams, M. A., Woelk, G. B., King, I. View abstract. Naylor CD, O'Rourke K, Detsky AS, Baker JP. J.Nutr. View abstract. 2006;47(12):5227-5233. View abstract. Brown L, Rimm EB, Seddon JM, et al. Effects of Lutein/Zeaxanthin Supplementation on the Cognitive Function of Community Dwelling Older Adults: A Randomized, Double-Masked, Placebo-Controlled Trial. Meta-Analysis of randomized controlled trials help reduce these symptoms 133 ( 1 ):452-65 oral! Not contain all possible interactions or adverse effects Williams lutein for eczema Wilkins, 1995 unaffected by alpha tocopherol beta., C. Protective effects of lutein and lycopene U. J plasma carotenoids and LDL oxidation in smokers lutein for eczema nonsmokers often... 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